What Is Polynucleotide Treatment?

Introduction to Polynucleotide Treatment

Polynucleotide treatment is a cutting-edge regenerative aesthetic procedure that is becoming increasingly popular in advanced skincare. It involves the precise injection of polynucleotides – long chains of nucleotides derived from purified salmon DNA – into the skin to stimulate tissue regeneration, improve elasticity, and promote a more youthful appearance. These naturally occurring biopolymers work on a cellular level, supporting the skin’s innate ability to heal and rejuvenate itself.

What Are Polynucleotides?

Polynucleotides are essential components of DNA and RNA, carrying genetic information and playing a key role in cellular function. When used in aesthetic treatments, they act as biostimulators. They signal skin cells – especially fibroblasts – to increase the production of collagen and elastin, two proteins critical for maintaining firmness, elasticity, and hydration. Unlike dermal fillers that temporarily add volume, polynucleotides address the underlying causes of ageing, encouraging long-term improvement in skin quality.

The Rise of Regenerative Skin Therapies

In recent years, the demand for treatments that provide subtle, natural-looking results has surged. Regenerative therapies like polynucleotide injections and PRP (platelet-rich plasma) are gaining popularity due to their ability to harness the body’s own repair mechanisms. These treatments do not freeze expressions or artificially volumise the face. Instead, they rejuvenate from within, offering patients a safer and more sustainable path to youthful skin.

How It Works

Polynucleotides are carefully injected into the dermal layer of the skin using microinjections. Once administered, they begin a multifaceted process of skin repair and regeneration:

• Stimulation of fibroblasts: These skin cells are activated to produce new collagen and elastin, improving structure and firmness.
• Deep hydration: Polynucleotides have a strong affinity for water molecules, allowing them to attract and retain moisture in the skin, improving overall hydration.
• Anti-inflammatory response: They reduce oxidative stress and inflammation, which are key contributors to ageing and skin sensitivity.

Scientific studies and clinical trials support the effectiveness of polynucleotide treatments. Patients report visible improvements in skin texture, tone, and elasticity after just a few sessions.

Key Benefits

Polynucleotide therapy offers a wide range of skin-enhancing benefits:

1. Skin Rejuvenation: Enhances natural radiance and promotes smoother, more youthful-looking skin.
2. Hydration and Texture: Binds moisture to the skin, reducing dryness and improving texture.
3. Elasticity and Firmness: Boosts the production of structural proteins that give skin its bounce and tightness.
4. Reduced Inflammation: Calms redness, irritation, and helps restore balance to compromised skin.
5. Post-Procedure Healing: Speeds up recovery when combined with other treatments like microneedling or lasers.

These benefits build progressively over the course of treatment and offer long-lasting improvements with proper maintenance.

Concerns It Can Treat

Polynucleotide treatments are incredibly versatile and suitable for various skin concerns:

• Fine lines and wrinkles: Softens expression lines and smooths deeper creases by improving collagen density.
• Acne scarring: Encourages tissue repair, gradually improving skin texture and reducing scar visibility.
• Dullness and dehydration: Revitalises tired-looking skin and restores healthy hydration levels.
• Under-eye puffiness and pigmentation: Reduces dark circles, puffiness, and crepey texture under the eyes.
• Sun damage and pigmentation: Promotes skin renewal, helping fade spots and repair UV-related damage.
• Sensitive or inflamed skin: Calms reactive skin and supports recovery in conditions such as rosacea.

Polynucleotide Treatment Process

Consultation and Procedure

Your polynucleotide journey begins with a personalised consultation with Dr Fasano. During this session, your skin will be assessed, and a customised treatment plan will be developed. The procedure itself is quick and minimally invasive, involving microinjections to target areas of concern. A numbing cream is typically applied beforehand to ensure comfort throughout the process.

Recovery and Aftercare

Following treatment, patients may experience mild redness, swelling, or bruising at the injection sites. These effects are temporary and usually resolve within 24-48 hours. To maximise results and minimise irritation, avoid touching the treated areas and refrain from vigorous exercise, alcohol, or heat exposure (like saunas) for at least one day.

Results Timeline

Visible improvements in hydration and texture may appear within the first week. However, full results develop gradually over 3-4 sessions spaced two to three weeks apart. As your skin continues to regenerate, improvements in elasticity and tone become more pronounced over the following weeks. Maintenance sessions every few months are recommended to sustain results.

Safety and Suitability

Polynucleotide treatments are considered very safe and well-tolerated when administered by trained professionals. Side effects are minimal and include temporary redness, mild swelling, or bruising. These typically subside quickly without complications.

This treatment is suitable for adults of all ages and skin types. It is especially beneficial for those seeking natural anti-ageing results, people with sensitive or damaged skin, or anyone wishing to boost overall skin health. However, it is not suitable for individuals who are pregnant, breastfeeding, or have active skin infections or autoimmune conditions.

Comparisons with Other Treatments

Understanding how polynucleotides compare to other skin treatments can help you choose the best option for your needs:

• Hyaluronic Acid Fillers: These add volume and hydrate the skin temporarily. While effective, they do not promote true regeneration like polynucleotides.
• PRP (Platelet-Rich Plasma): Uses your own blood to stimulate collagen production, but outcomes can vary due to patient variability. Polynucleotides provide more consistent, controlled results.
• Microneedling/Mesotherapy: These methods improve skin texture and deliver active ingredients, but polynucleotides work deeper at the cellular level to stimulate regeneration.

FAQs

• How long do results last? Results typically last between 6 and 12 months, depending on individual factors like age, skin condition, and lifestyle. Maintenance sessions are advised for continued improvement.
• Is it suitable for all skin types? Yes. Polynucleotide treatments are safe for all skin types, including darker tones and sensitive skin.
• How many sessions are needed? Most patients benefit from an initial course of 3 to 4 sessions, spaced 2-3 weeks apart. Maintenance sessions every 3-6 months help prolong results.
• Can it be combined with other treatments? Yes. It pairs well with treatments like microneedling, lasers, Botox, and dermal fillers to enhance outcomes.
• What is the cost? Pricing varies based on treatment area, number of sessions, and individual needs. A tailored quote is provided during your consultation.

Why Choose Dr Fasano?

Dr Fasano is a renowned expert in regenerative and aesthetic medicine. With years of experience and a deep understanding of cellular therapies, he delivers customised treatments that prioritise safety, efficacy, and patient satisfaction.

At his state-of-the-art clinic, you can expect a warm, professional atmosphere, cutting-edge equipment, and a personalised care plan designed to meet your unique skin goals. His patients consistently report high satisfaction and visible, natural results.

Recap

Polynucleotide treatment is a powerful, scientifically-backed solution for improving skin health and reversing the visible signs of ageing. By working with your body’s natural healing processes, it offers a safe, effective, and long-term approach to skin rejuvenation.

Whether you’re concerned about fine lines, dehydration, or dullness, this regenerative therapy could be the key to refreshed, radiant skin. Book a consultation with Dr Fasano today to explore how polynucleotide treatment can transform your complexion from within.